We have been made aware that desmopressin 10 microgram/dose nasal spray is out of stock, with an anticipated re-supply date of early September 2025.

There are alternative preparations of desmopressin medication that are widely available, including:

  • Desmopressin 100 and 200 microgram tablets
  • Desmopressin sublingual tablets
  • DDAVP Melt oral lyophilisates (60, 120 and 240 microgram)

The switch from the nasal spray to an oral formulation should be overseen by your endocrinology team. Contact your endocrine team before you run out of supply to ensure that an appropriate alternative (including appropriate dose) is recommended to your GP for prescribing.

The Pituitary Foundation very much understand the concern that this supply issue is causing for our community. We are monitoring this and will be updating our website with any further news that we receive.

What is desmopressin?

Desmopressin is a medication used for the treatment of AVP deficiency. You can read more about what desmopressin is, and how it is used, on our AVP deficiency treatment page.