Kallmann syndrome is a form of hypogonadotropic hypogonadism (HH). The condition is characterised by an absence or failure to respond to GnRH, a hormone normally released by the hypothalamus.
Men or women affected with Kallmann syndrome, or HH, fail to go through puberty and are normally infertile. People with Kallmann syndrome also have the additional symptom of a lack of sense of smell (anosmia).
Treatment is available via hormone replacement therapy or gonadotropin treatment to restore fertility.